Table 1.

Advantages and disadvantages of different nanoparticles as delivery systems

	Nanoparticle	Advantages	Disadvantages
Lipid based	Liposomes SLN Emulsions	Formulation simplicity High bioavailability Payload flexibility Biodegradable Biocompatible	Low encapsulation efficiency Poor stability Leakage May trigger immune response
Polymer based	Nanocrystals Nanospheres Polymersomes Dendrimers	Biodegradable Payload flexibility Precise control of characteristics Easy surface modification	Possibility of aggregation Toxicity Low cell affinity
Inorganic based	AuNP AgNP Iron oxide Quantum dots	Unique electrical, optical, and magnetic properties Variable size, structure, and geometry Easy functionalization	Poor solubility Toxicity