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. 2023 Feb 3;14:1060540. doi: 10.3389/fimmu.2023.1060540

Table 1.

Surface Plasmon Resonance (SPR) readout for the bivalent interactions of anti-PD-L1 clones 12F1-1 and 11B12-1 with hamster PD-L1.

12F1-1 11B12-1
Bmax1 310.13 167.60
Ka1 (1/M x s) 2.08 x 1012 2.12 x 102
Kd1 (1/s) 6.34 x 10-14 3.08 x 10-14
KD1 (M) 3.05 x 10-16 1.45 x 10-16
Bmax2 82.69 23.38
Ka2 (1/M x s) 1.10 x 103 3.47 x 104
Kd2 (1/s) 1.45 x 10-2 3.22 x 10-4
KD2 (M) 1.32 x 10-5 9.27 x 10-9