Skip to main content
. Author manuscript; available in PMC: 2023 Sep 1.
Published in final edited form as: Nat Rev Endocrinol. 2022 Nov 29;19(3):134–150. doi: 10.1038/s41574-022-00773-5

Fig 6. Environmental factors influencing tumor initiation.

Fig 6.

Many systemic and local factors related to metabolism have the potential to alter process related to tumor initiation. Hypoxia and inflammation likely favor tumor growth. Diet, nutrient availability, and microbial homeostasis may potentiate or antagonize tumor initiation and progression. Importantly, these processes are all interconnected and likely to affect many cell types with the potential to alter tumor progression.