Table 3.
Independent Risk Factors of Hypoxic-Ischemic Encephalopathy in Neonates Born to Women with or without Previous Childbearing History
| Variables | Newborns Born to Women without Previous Childbearing History | Newborns Born to Women with Previous Childbearing History | ||
|---|---|---|---|---|
| Adjusted OR (95% CI) | P value | Adjusted OR (95% CI) | P value | |
| Gender | ||||
| Male | 1.000 (Reference) | 1.000 (Reference) | ||
| Female | 0.966 (0.224–4.162) | 0.963 | 1.507 (0.109–20.741) | 0.759 |
| Mode of delivery | ||||
| Spontaneous | 1.000 (Reference) | 1.000 (Reference) | ||
| Cesarean section | 0.722 (0.140–3.715) | 0.697 | 0.541 (0.048–6.116) | 0.619 |
| Gestational age (weeks) | ||||
| 37–42 | 1.000 (Reference) | 1.000 (Reference) | ||
| <37 | 1.391 (0.108–17.971) | 0.800 | / | 0.994 |
| Birth weight (kg) | ||||
| <2.5 | 1.068 (0.009–3.216) | 0.236 | / | 0.994 |
| 2.5–4.0 | 1.000 (Reference) | 1.000 (Reference) | ||
| >4.0 | / | 0.999 | 7.085 (0.182–275.369) | 0.294 |
| Adverse pregnancy history | ||||
| Yes | / | / | 1.000 (Reference) | |
| No | / | / | 0.650 (0.090–4.682) | 0.669 |
| Perinatal conditions | ||||
| Amniotic fluid contamination | ||||
| No | 1.000 (Reference) | 1.000 (Reference) | ||
| Yes | 5.695 (1.345–24.120) | 0.018 | 1.044 (0.112–9.728) | 0.970 |
| Nuchal cord | ||||
| No | 1.000 (Reference) | 1.000 (Reference) | ||
| Yes | 0.180 (0.030–1.091) | 0.062 | 1.194 (0.086–16.650) | 0.895 |
| Placenta abnormality | ||||
| No | 1.000 (Reference) | 1.000 (Reference) | ||
| Yes | / | 0.999 | / | 0.998 |
| 1-minute Apgar score | ||||
| >3 | 1.000 (Reference) | 1.000 (Reference) | ||
| ≤3 | 32.518 (3.326–317.891) | 0.003 | / | 0.992 |
| 5-minute Apgar score | ||||
| >7 | 1.000 (Reference) | 1.000 (Reference) | ||
| ≤7 | 15.411 (2.570–92.417) | 0.003 | / | 0.995 |