Figure 4.

Imaging example of SI variation within the normal myocardium that affected the performance of the STRM quantification method, in particular for conventional bright-blood LGE when using thresholds >5 SDs. Although the reference region (green) is consistently positioned in the septum for both LGE methods, notable differences in infarct size (purple) are observed between both methods when using higher thresholds for the STRM method. Since the FWHM method uses the maximum SI instead of reference region in remote myocardium, its performance is less sensitive to local SI variations and therefore performs well in this case. Note that the same endo- (red) and epicardial (blue) contours have been used for all quantification techniques for each LGE method.