Table 2. Effect of taurine, piracetam and vinpocetine on changes in body and brain weight of rats treated with ETP.
| Group | Control | ETP | ETP + TAU | ETP + PIR | ETP + VIN |
|---|---|---|---|---|---|
| Initial body weight (g) | 184.5 ± 6 | 193.8 ± 6.25 | 172.8 ± 3.4 | 186.8 ± 6 | 172 ± 4.7 |
| Final body weight (g) | 192 ± 5 | 180.8 ± 7 | 187 ± 3.4 | 199.8 ± 6.48 | 183 ± 4.5 |
| Body weight change (g) | 7.5 ± 2.2b | −13 ± 1.2a | 14.25 ± 2.3b | 13 ± 3b | 11 ± 4.4b |
| Body weight change (%) | 4.1 ± 1.3b | −6.8 ± 0.8a | 8.3 ± 1.4b | 7 ± 1.7b | 6.5 ± 2.7b |
| Brain weight | 2.8 ± 0.04 | 2.9 ± 0.05 | 2.9 ± 0.01 | 2.9 ± 0.04 | 2.8 ± 0.05 |
| Relative brain weight (%) | 1.5 ± 0.04 | 1.6 ± 0.08 | 1.6 ± 0.05 | 1.4 ± 0.06 | 1.6 ± 0.05 |
All values are expressed as mean ± SEM
Different signs indicate significances
a
p < 0.05 significantly different when compared with control group
b
p < 0.05 significantly different when compared with ETP group
Missed signs of significances indicate statistically non-significant groups
ETP, Etoposide; TAU, Taurine; PIR, Piracetam; VIN, Vinpocetine