Table 3. Semi-quantitative scoring of histopathological alterations in the brains of different groups.
| Histopathological alterations in the brain | Experimental groups | ||||
|---|---|---|---|---|---|
| Control | ETP | ETP + TAU | ETP + PIR | ETP + VIN | |
| Necrosis of neurons | 0 | 2 | 0 | 0 | 0 |
| Pyknosis of neurons | 0 | 2 | 1 | 1 | 1 |
| Gliosis | 0 | 2 | 1 | 1 | 1 |
| Gemistocytic change | 0 | 2 | 0 | 0 | 1 |
| Astrocyte proliferation | 0 | 2 | 0 | 0 | 0 |
| Bony metaplastic change with calcification | 0 | 2 | 0 | 0 | 0 |
| Oedema and vascular congestion | 0 | 2 | 1 | 1 | 1 |
ETP, Etoposide; TAU, Taurine; PIR, Piracetam; VIN, Vinpocetine