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CNPs activated the expression of Nrf2 and related antioxidant genes in TMJ-OA chondrocytes. Expression of (A) Nrf2, HO-1, and (B) downstream key endogenous antioxidant genes. (C) Protein expression levels of Nrf2 and HO-1. (D) Semi-quantitative analysis of (C). (E) Nrf2 nuclear translocation was detected using immunofluorescence (original magnification). *p <0.05. **p <0.01. ***p <0.001.
