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. 2023 Feb 15;10(2):ENEURO.0361-22.2023. doi: 10.1523/ENEURO.0361-22.2023

Figure 1.

Figure 1.

Long photoperiod increases evoked dopamine release in the NAc core. A, Light cycles for Short, Equinox, and Long photoperiod conditions exposed to mice from embryonic day 0 (E0) until they were used for voltammetry at postnatal day 50 (P50). B, Sagittal slices containing the NAc core were collected from each animal. C, Placement of stimulating and recording electrodes in the NAc core. D, Representative current trace and voltammogram. E, Representative traces and color plots for mice raised in Short, Equinox, and Long photoperiods. F, Evoked NAc core dopamine release across tonic and phasic frequencies in male (open symbols) and female (closed symbols) mice raised in Short (N = 9), Equinox (N = 12), and Long (N = 10) photoperiods. Main effect of photoperiod (F(2,115) = 10.43, p < 0.0001), stimulation frequency (F(3,115) = 13.18, p < 0.0001). *p < 0.05 for Long versus Equinox. Data were analyzed using two-way ANOVA and Tukey’s post hoc multiple comparisons test with an α value of p = 0.05. Data are represented as mean ± SEM.