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. Author manuscript; available in PMC: 2024 Jan 10.
Published in final edited form as: Adv Funct Mater. 2022 Nov 7;33(2):2209971. doi: 10.1002/adfm.202209971

Figure 3.

Figure 3.

Quantitative and qualitive determination of DNNA adhesion performances. (A) Force-displacement curves of HA-Cat, fibrin, HA-TU-Cat, and DNNA under lap shear measurement through fresh porcine skins. Inset: Illustration of the lap shear measurement. (B) Shear adhesion strength of HA-Cat, fibrin, HA-TU-Cat, and DNNA (n=3–4). (C) Force-displacement curves of HA-Cat, fibrin, HA-TU-Cat, and DNNA under tensile measurement through rabbit sciatic nerves. Inset: Illustration of the tensile measurement. (D) Tensile adhesion strength of HA-Cat, fibrin, HA-TU-Cat, and DNNA (n=3–5). (E) Qualitive adhesion evaluation of DNNA through rabbit sciatic nerves. Rabbit nerve was cut into three parts (a); The transected nerves were successfully connected by DNNA (b); In situ rabbit nerve adhesion (c). (F) Qualitive adhesion evaluation of DNNA under deformations and wet environments. DNNA (with green food dye) formed on porcine skin in situ was twisted and soaked in PBS for 30 min (a); DNNA formed on the porcine skin in situ was flushed continuously for 5 min (b); DNNA formed on the glass slide in situ was flushed continuously for 5 min (c). All quantitative data are expressed as the mean ± standard deviation. Asterisks indicate statistically significant comparisons, with *p < 0.05 and **p < 0.01, by Student’s t-test or one-way ANOVA with Tukey’s multiple comparisons tests.