Sensory and motor function recovery of rats with transected nerve injuries. (A) Mechanical sensory functions of rats tested by a von Frey test over time (n=6). (B) Thermal sensory functions of rats tested by a Hargreaves test over time (n=6). #: p<0.001 between DNNA and Fibrin; @: p<0.05 between DNNA and Fibrin. (C) Footprints were captured by a rat-walking apparatus, and the foot pressure ratio was calculated as LH/RH at 10 weeks after surgery (n=3). (D) Stance trace of rats at 10 weeks after operation. (E) Perpendicular AEP and PEP ratios (LH/RH) demonstrating body wobble (6–10 steps from 3 rats in each group). (F) Stance/swing durations of each group and their ratios of experimental foot to healthy foot (LH/RH, 6–10 steps from 3 rats in each group). All quantitative data are expressed as the mean ± standard deviation. Asterisks indicate statistically significant comparisons, with *p < 0.05, **p < 0.01, and ***p < 0.001, by Student’s t-test or one-way ANOVA with Tukey’s multiple comparisons tests.