Appendix 1—table 2. Performance comparison of BEN with SOTA methods on the source domain (Mouse-T2WI-11.7T).

Dice: Dice score; SEN: sensitivity; SPE: specificity; ASD: Average Surface Distance; HD95: the 95-th percentile of Hausdorff distance.

Method	Dice	SEN	SPE	ASD	HD95
Sherm	0.9605	0.9391	0.9982	0.6748	0.4040
AFNI	0.9093	0.9162	0.9894	1.9346	0.9674
FSL	0.3948	1.0000	0.6704	20.4724	5.5975
BEN	0.9859	0.9889	0.9982	0.3260	0.1436