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Schematic representation of various regulatory mechanisms of CBXs in cancer. CBX, chromobox; PPI, protein-protein interaction; Ub, ubiquitin; PTM, posttranslational modification; ncRNA, noncoding RNA; lncRNA, long noncoding RNA; miRNA, microRNA; circRNA, circular RNA; ORF, open reading frame; H3K27me3, histone H3 lysine K27 trimethylation.
