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. 2022 Dec 7;28:182–196. doi: 10.1016/j.omto.2022.12.002

Figure 5.

Figure 5

In vivo biodistribution of homologous targeting m-PPDCNPs

(A) Overlaid Cy7 fluorescent image of the HCT116 xenograft tumor-bearing nude mice 0 h, 4 h, 8 h, 12 h and 24 h post-injection of naked miR-190-Cy7, PPDCNPs, and m-PPDCNPs. (B) Overlaid Cy7 fluorescent image of the tumors and main organs of the HCT116 xenograft tumor-bearing nude mice sacrificed 24 h post-injection of naked miR-190-Cy7, PPDCNPs, and m-PPDCNPs. Li: liver, S: Spleen, K: Kidney, H: Heart, Lu: lung, T: tumor. (C) Biodistribution of the naked miR-190-Cy7, PPDCNPs, and m-PPDCNPs quantified from (B).