Table 2.
Kaplan‒Meier plots evaluating the OS of CRC and its PTL as a function of seven prognostic factors (STK1p, CEA, CA19.9, TNM stage, pathological grade, age and sex)
| Item | Log-rank test (P-value) | X2 |
|---|---|---|
| A. CRC | ||
| 1. STK1p, ≤ 0.9 vs. > 0.9 pM | 0.003 | 15.371 |
| 2. CEA, ≤ 5 vs. > 5 ng/ml | 0.000 | 26.715 |
| 3. CA19.9, ≤ 35 vs. > 35 ng/ml | 0.000 | 34.834 |
| 4. TNM stage, I + II vs. III | 0.000 | 54.093 |
| 5. Pathological grades, G1 + G2 vs. G3 | 0.005 | 8.057 |
| 6. Age, > 60 ≤ 60 ys. | 0.035 | 4.42 |
| 7. Sex, F. vs. M | 0.033 | 4.566 |
| B. R-CC | ||
| 1. STK1p, ≤ 0.9 vs. > 0.9 pM | 0.051 | 3.794 |
| 2. CEA, ≤ 5 vs. > 5 ng/ml | 0.154 | 2.073 |
| 3. CA19.9, ≤ 35 vs. > 35 ng/ml | 0.113 | 2.509 |
| 4. TNM stage, I + II vs. III | 0.006 | 7.476 |
| 5. Pathological grades, G1 + G2 vs. G3 | 0.188 | 1.73 |
| 6. Age, > 60 ≤ 60 ys. | 0.671 | 0.18 |
| 7. Sex, F. vs. M | 0.667 | 0.185 |
| C. L-CC | ||
| 1. STK1p, ≤ 0.9 vs. > 0.9 pM | 0.037 | 4.371 |
| 2. CEA, ≤ 5 vs. > 5 ng/ml | 0.054 | 3.726 |
| 3. CA19.9, ≤ 35 vs. > 35 ng/ml | 0.067 | 3.352 |
| 4. TNM stage, I + II vs. III | 0.000 | 12.332 |
| 5. Pathological grades, G1 + G2 vs. G3 | 0.256 | 1.241 |
| 6. Age, > 60 ≤ 60 ys. | 0.027 | 4.915 |
| 7. Sex, F. vs. M | 0.108 | 2.586 |
| D. RC | ||
| 1. STK1p, ≤ 0.9 vs. > 0.9 pM | 0.002 | 9.401 |
| 2. CEA, ≤ 5 vs. > 5 ng/ml | 0.000 | 25.189 |
| 3. CA19.9, ≤ 35 vs. > 35 ng/ml | 0.000 | 38.996 |
| 4. TNM stage, I + II vs. III | 0.000 | 34.554 |
| 5. Pathological grades, G1 + G2 vs. G3 | 0.03 | 8.708 |
| 6. Age, > 60 ≤ 60 ys. | 0.119 | 2.433 |
| 7. Sex, F. vs. M | 0.156 | 2.01 |
Black bold: P-values of < 0.05 were considered statistically significant