Table 4.
COX multivariate analysis for OS of CRC (A), R-CC (B), L-CC (C) and RC (D)
| COX multivariate analysis | Hazard risk | 95% CI | p value |
|---|---|---|---|
| A. CRC | |||
| STK1p, ≤ 0.9 vs. > 0.9 pM | 1.828 | 1.242–2.691 | 0.002 |
| CEA, ≤ 5 vs. > 5 ng/ml | 1.539 | 1.539–1.102 | 0.013 |
| CA19.9, ≤ 35 vs. > 35 ng/ml | 2.474 | 1.664–3.677 | 0.000 |
| TNM stage, I + II vs. III | 2.839 | 2.893–2.024 | 0.000 |
| Pathological grades, G1 + G2 vs. G3 | 1.68 | 1.128–2.503 | 0.011 |
| Age, > 60 ≤ 60 ys. | 1.666 | 1.171–2.370 | 0.005 |
| Sex, F. vs. M. | 0.675 | 0.463–0.982 | 0.04 |
| B. R-CC | |||
| TNM stage, I + II vs. III | 3.139 | 1.30–7.582 | 0.011 |
| C. L-CC | |||
| TNM stage, I + II vs. III | 4.168 | 1.980–8.852 | 0.000 |
| D. RC | |||
| STK1p, ≤ 0.9 vs. > 0.9 pM | 1.777 | 1.094–2.753 | 0.031 |
| CEA, ≤ 5 vs. > 5 ng/ml | 2.716 | 1.796–4.382 | 0.000 |
| CA19.9, ≤ 35 vs. > 35 ng/ml | 2.119 | 1.293–3.472 | 0.003 |
| TNM stage, I + II vs. III | 2.716 | 1.796–4.382 | 0.000 |
Black bold: P-values of < 0.05 were considered statistically significant