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. 2023 Feb 17;14:919. doi: 10.1038/s41467-023-36634-6

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — This refers to 'any process that decreases the frequency, rate or extent of centrosome duplication'. a Representative examples of each of the indicated cell lines. Centrioles were detected by staining with gamma-tublin (γ-tub), nuclei were stained with DAPI. Asterisks indicate cells with more than two centrioles. The Hoik-1, Sehp-2 and Kegd-2 were control cell lines. b Histogram showing the percentage of cells with more than 2 centrioles per cell in the indicated cell lines. Results are summarised as the mean ± s.e.m. from 3 independent experiments (600-800 cells per cell line were analysed; each percentage from each experiment were shown as dots; *: P < 0.05; **: P < 0.005; ns: not significant). Specifically, the p-values are: Boqx-2 P = 0.045, Suul-1 P = 0.0021, Yoch-6 P = 0.0023 (one-sided t-test).