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. 2022 Dec 15;128(4):568–575. doi: 10.1038/s41416-022-02072-2

Table 2.

Logistic regression analysis of decreased tumour-infiltrating lymphocytes.

Univariate p value Multivariate p value
OR 95% CI OR 95% CI
Age (≥65 vs. <65) 0.74 0.25–2.21 0.59
Tumour size (≥pT2 vs. <pT2) 2.04 0.83–4.99 0.12
Nodal status (positive vs. negative) 2.36 0.97–5.75 0.06
Subtype (TNBC vs. others) 1.39 0.57–3.41 0.47
HG (3 vs. 1–2) 6.53 2.18–19.6 0.001 5.71 1.75–18.06 0.004
RFI (≥median vs. <median) 0.66 0.27–1.59 0.36
Site of recurrence (distant vs. locoregional) 0.97 0.38–2.52 0.96
Adjuvant CT (yes vs. no) 7.65 2.77–21.1 <0.001 6.85 2.34-20.08 <0.001
Adjuvant RT (yes vs. no) 1.54 0.64–3.73 0.34
Adjuvant HT (yes vs. no) 1.39 0.58–3.35 0.46

CT chemotherapy, CI confidence interval, HG histological grade, HT hormone therapy, RT radiotherapy, RFI recurrence-free interval, OR odds ratio, RT radiotherapy, RFI recurrence-free interval, OR odds ratio, TNBC triple-negative breast cancer, TIL tumour-infiltrating lymphocyte.