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. 2022 Dec 23;128(3):413–418. doi: 10.1038/s41416-022-02109-6

Fig. 2. Distribution of doxorubicin in solid tumours.

Fig. 2

a Distribution of fluorescent doxorubicin (false-colour blue) around blood vessels (recognised by CD31 on endothelial cells: false-colour red) in a mouse mammary tumour. Hypoxic areas are recognised by binding to EF5 (false-colour green). b Doxorubicin fluorescence as a function of distance from the nearest blood vessel in sections from three mouse mammary tumours. Modified from Primeau et al. [16].