Table 3.
Top Canonical Pathways differentially expressed in the soleus of ERRβ/γ dmKO mice and their Rank and P-value in all ERR KO lines.
| Canonical pathways | ERRα/γ dmKO |
ERRα mKO |
ERRβ/γ dmKO |
|||
|---|---|---|---|---|---|---|
| Rank | P-Value | Rank | P-Value | Rank | P-Value | |
| Fatty Acid β-oxidation | #6 | 4.9E-06 | NA | – | #1 | 4.6E-08 |
| Valine Degradation | #4 | 3.4E-09 | NA | – | #2 | 8.3E-08 |
| Glutaryl-CoA Degradation | #15 | 4.1E-04 | NA | – | #3 | 7.8E-07 |
| Tryptophan Degradation | #11 | 1.0E-04 | #293 | 0.5 | #4 | 1.5E-06 |
| Isoleucine Degradation | #7 | 9.5E-06 | NA | – | #5 | 3.6E-06 |
| Ethanol Degradation II | #30 | 1.2E-02 | NA | – | #6 | 7.4E-06 |
| Ethanol Degradation IV | #44 | 2.5E-02 | NA | – | #7 | 3.4E-05 |
| Ketolysis | #21 | 2.2E-03 | NA | – | #8 | 3.9E-05 |
| Oxidat. Ethanol Degrad. III | #48 | 3.8E-02 | NA | – | #9 | 9.5E-05 |
NA, non-applicable; these pathways were not identified as regulated in ERRα mKO soleus. For ERRβ/γ dmKO EDL, only pathways with p < 1 × 10E-4 are shown.