Table 2.
Results of discrete-time hazard models for influenza and pneumonia, chronic lower respiratory diseases and Alzheimer’s disease
Influenza and pneumonia (n = 29) | Chronic lower respiratory disease (n = 66) | Alzheimer’s disease (n = 38) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Predictor | β | SE | p | Hazard | β | SE< | p | Hazard | β | SE | p | Hazard |
ratio (95% CIs) | ratio (95% CIs) | ratio (95% CIs) | ||||||||||
Age Spline-1 | 0.20 | 0.39 | 0.60 | 1.22 (0.57, 2.63) | 0.15 | 0.46 | 0.74 | 1.17 (0.47, 2.89) | 0.49 | 0.26 | 0.07 | 1.63 (0.97, 2.71) |
Age Spline-2 | −1.04 | 0.69 | 0.13 | 0.35 (0.09, 1.35) | −0.05 | 1.20 | 0.96 | 0.95 (0.09, 9.88) | −0.95 | 0.61 | 0.12 | 0.39 (0.12, 1.27) |
Age Spline-3 | 6.02 | 0.93 | <0.001*** | 410.76 (66.20, 2548.82) | 2.50 | 1.75 | 0.16 | 12.19 (0.40, 374.64) | 4.64 | 0.89 | <0.001*** | 103.60 (17.94, 598.22) |
Testosterone | −0.06 | 0.10 | 0.54 | 0.94 (0.77, 1.15) | −0.23 | 0.13 | 0.09 | 0.80 (0.61, 1.03) | −0.21 | 0.11 | 0.05† | 0.81 (0.66, 1.00) |
African American | −0.02 | 0.51 | 0.97 | 0.98 (0.36, 2.65) | −1.49 | 0.51 | 0.005** | 0.22 (0.08, 0.61) | −1.76 | 0.64 | 0.01** | 0.17 (0.05, 0.60) |
Other Ethnicity | 0.27 | 0.89 | 0.76 | 1.31 (0.23, 7.46) | 0.08 | 0.56 | 0.88 | 1.09 (0.37, 3.24) | −15.43 | 0.20 | <0.001*** | 0.00 (0.00, 0.00) |
Hispanic/Latino | 0.29 | 0.68 | 0.67 | 1.33 (0.35, 5.05) | 0.23 | 0.42 | 0.59 | 1.25 (0.56, 2.83) | −0.40 | 0.57 | 0.48 | 0.67 (0.22, 2.05) |
Education | −0.58 | 0.25 | 0.02* | 0.56 (0.34, 0.92) | −0.61 | 0.18 | <0.001*** | 0.54 (0.38, 0.77) | −0.25 | 0.23 | 0.29 | 0.78 (0.49, 1.23) |
Body Mass Index | 0.01 | 0.04 | 0.84 | 1.01 (0.94, 1.08) | 0.03 | 0.05 | 0.49 | 1.03 (0.94, 1.14) | −0.12 | 0.04 | 0.01** | 0.89 (0.82, 0.97) |
Age 1*Testosterone | −0.16 | 0.08 | 0.06† | 0.85 (0.73, 1.00) | −0.14 | 0.08 | 0.09 | 0.87 (0.75, 1.02) | −0.22 | 0.05 | <0.001*** | 0.81 (0.73, 0.89) |
Age 2*Testosterone | 0.49 | 0.16 | 0.004** | 1.62 (1.18, 2.24) | 0.23 | 0.21 | 0.29 | 1.26 (0.83, 1.91) | 0.38 | 0.12 | 0.002** | 1.46 (1.16, 1.85) |
Age 3*Testosterone | −0.74 | 0.25 | 0.005** | 0.48 (0.29, 0.78) | 0.08 | 0.34 | 0.82 | 1.08 (0.55, 2.11) | −0.18 | 0.17 | 0.27 | 0.83 (0.60, 1.15) |
Note. Lower testosterone levels are associated with higher risk of death in men.
*p < 0.05, **p < 0.01, ***p < 0.001, †p < 0.06.