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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Trends Biotechnol. 2022 Aug 19;41(4):511–527. doi: 10.1016/j.tibtech.2022.07.011

Figure 1. Different models for investigating synovial joint diseases with varying throughput and complexity.

Figure 1

Currently, throughput and complexity/physiological relevance are, in most cases, mutually preclusive. Therefore, a trade-off between throughput and complexity is usually made when selecting a specific model. Depending on the design and application, joint-on-a-chip platforms can possess a wide range of throughput and complexity. 2D: two-dimensional; 3D: three-dimensional; Ref.: references.