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. 2023 Feb 18;14:929. doi: 10.1038/s41467-023-36614-w

Fig. 8. Graphic summary of the mechanisms for GSDME accelerating inflammatory response in atherosclerosis.

Fig. 8

Transcriptional activation and the upregulated GSDME augment the activity of caspase 3 and promote apoptosis converts to pyroptosis in macrophages during the process of atherosclerosis.