Figure 1. Conceptual Definition of Geriatric Syndrome.

Geriatric syndromes result from the cumulative, synergistic effects of discrete diseases on multiple organ systems; when the body can no longer compensate, the effects are finally expressed as a single symptom. The cumulative system impairments result in impaired function. When these impairments accumulate or when additional stress is present, function is lost and a geriatric syndrome develops. The accumulation of geriatric syndromes leads to an overall premorbid state (ie, frailty).