TABLE 1.

From three profile datasets, 217 differentially expressed genes were discovered, including 110 co‐upregulated genes and 107 co‐downregulated genes in DCIS

DEGs	Genes name
Upregulated	ATP2A2, POLE2, MELK, MAPKAPK2, P4HA3, BCOR, NEK2, TRIB3, VCAN, CXCL10, PDE7A, DHCR7, HOOK1, SLC20A1, TNC, PLEK2, B3GNT2, BDH1, CTHRC1, PTPN3, HNRNPH1, EFNA3, PAICS, CXADR, EPCAM, AFG3L2, SNRNP40, MTA1, PRCP, P4HA1, CDKN3, PHTF1, GTF3C2, ABI2, PABPC1, NUP210, STIP1, UBE2A, DEPDC1, POLR2H, CDH2, PAX5, YAF2, HNRNPA2B1, CUTA, MAPK8, BIRC5, IDH2, SCO2, DGKD, EMP2, CALU, DTL, PPAT, RPN2, CD44, NOP2, GALNT3, NRAS, TJP3, RFX5, CKAP4, GSS, CCT5, COL1A1, DDX31, ULK3, FBXO28, SLC45A4, TRA2B, KYNU, ACSL3, GPD2, TFDP1, RAB11A, SFPQ, TMPO, FGFR2, MYB, CREM, BCL2L11, SFI1, SLC35A2, BID, SPDL1, MTDH, EFS, ADAM12, COL1A2, MDM2, CYFIP2, REL, ACVR1B, GAPDH, TNFSF4, NUDCD1, ICA1, SRPK1, ZSCAN12, AREG, CUX1, AREL1, RIT1, PAIP1, RNF4, TFEC, SLC35D1, IFT80, AGR2, LMNB2
Downregulated	PCM1, CA3, SNX6, LIMCH1, TSC22D3, SNX2, PEPD, MYLK, HDAC7, HYAL1, RAP1B, KLF4, COL4A1, ARID4A, FOS, PALM, PHF11, ACKR3, TMEM218, KL, DNAJC18, MITF, MTHFD1, FYN, CD14, ADCY6, LYVE1, IL15RA, CTNNA1, TMEM255A, FOLR2, FKBP5, PTPN11, DCUN1D4, SLC40A1, LAMA3, RAB30, CDH13, STAB1, ING4, SCN4A, IFFO1, PDXK, DCN, MECOM, WDR45, SGK2, DHX38, HBB, DHDDS, KRIT1, EPHA3, ME3, EHBP1, SGCB, DGKZ, SEC22A, RUNX1T1, UGP2, PRPF31, FOSB, SCN9A, MAP1A, NCOR1, HNMT, ACSS2, ATXN3, RBP4, OGG1, CASP4, TEAD1, SORBS3, MEF2C, DENND3, ASMTL, ZHX1, SNTB2, CDON, CDIP1, ACTR3, SCUBE2, RPS6KA2, DYNC1I2, NFU1, CLU, MYO1C, ST3GAL6, ITGB5, CLDND1, OXTR, LY6K, TMCC1, RASSF8, ATP1A2, HEXA, USP24, SLC41A3, EXOC3, AADAC, PPBP, CYTH3, SNCA, HSD17B14, USP47, COLGALT2, IK, PCDH19