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Signal detection for PARPi‐associated hematological toxicities
| PARPI | N | ROR (95% CI) | PRR (χ2) | IC (IC025) | EBGM (EBGM05) |
|---|---|---|---|---|---|
| All PARPIs | 4088 | 4.09 (3.95–4.23) | 3.56 (7845.89) | 1.82 (1.77) | 3.54 (3.42) |
| Olaparib | 1350 | 5.32 (5.01–5.64) | 4.40 (3720.16) | 2.14 (2.04) | 4.39 (4.14) |
| Niraparib | 1821 | 3.92 (3.73–4.13) | 3.44 (3300.2) | 1.78 (1.70) | 3.43 (3.26) |
| Rucaparib | 766 | 2.82 (2.61–3.04) | 2.59 (785.04) | 1.37 (1.26) | 2.59 (2.40) |
| Talazoparib | 151 | 9.81 (8.07–11.92) | 6.89 (798.75) | 2.78 (2.45) | 6.89 (5.67) |
