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. 2022 May 21;13(1):192–203. doi: 10.1016/j.apsb.2022.05.018

Figure 5.

Figure 5

Fenofibrate rescued the declined FA β-oxidation relative pathway in CS-Dsg2−/− mice. (A) Results of quantitative PCR analysis for Dsg2, Cd36, Atgl, Pparα, Pgc1α, Cpt1b, Acox1, Acadm, Acadl and Acadvl mRNA levels are expressed as fold change of control using β-actin as loading control. (B) Representative Western blots of DSG2, pmTOR, mTOR, p4EBP1, 4EBP1, PPARα, PGC1α, CPT1b, ACADL and GAPDH. Fatty acid oxidation rate (C) and ATP content (D) of heart. Results are expressed as mean values ± SEM. n = 5–7. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001.