Table 3.
Threshold effect analysis for the relationship between visceral adiposity index (VAI) and serum anti-aging protein klotho in NHANES 2007–2016a.
| Model | serum klotho protein concentration | |
|---|---|---|
| Adjusted β (95% CI) | P value | |
| Model I | ||
| the standard linear mode | -7.84 (-13.02, -2.65) | 0.0030 |
| Model II | ||
| Turning point (K) | 3.21 | |
| VAI < 3.21 (accounting for 83.7% of the participants) | -18.61 (-28.87, -8.35) | 0.0004 |
| VAI > 3.21 (accounting for 16.3% of the participants) | 1.40 (-7.79, 10.59) | 0.7652 |
| Log likelihood ratio test | 0.017 | |
a
All models were adjusted for gender, age, race, poverty income ratio, body mass index, education, marital status, physical activity, smoking, alcohol use, chronic kidney disease, cancer, diabetes, hypertension, stroke, chronic obstructive pulmonary disease, and cardiovascular disease.