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Metabolic pathway analysis (MetPA) analysis of differential metabolites for the (A) middle cerebral artery occlusion (MCAO) versus sham, (B) MCAO/reperfusion (R) versus sham, and (C) MCAO/R versus MCAO groups. The -ln p-value on the y-axis and the size of each circle were obtained from the pathway enrichment analysis, while the impact values on the x-axis were from the pathway topology analysis.
