Table 1.
Basic clinicopathologic data for metastatic colorectal cancers.
| Characteristics | Category | N (%) |
|---|---|---|
| Age | Mean [years (SD)] | 58.3 (9.9) |
| Range | 30–79 | |
| Sex | Male | 84 (75.7) |
| Female | 27 (24.3) | |
| ECOG PS | 0 | 17 (15.3) |
| 1 | 53 (47.7) | |
| 2 | 28 (25.2) | |
| 3 | 13 (11.8) | |
| Diameter of primary tumours | Median [cm (IQR)] | 4.0 (2.1) |
| Range | 1.3–10.0 | |
| Diameter of paired metastases | Median [cm (IQR)] | 2.0 (2.0) |
| Range | 0.6–20 | |
| Primary tumour location | Right colon cancer | 26 (23.4) |
| Left colon cancer | 85 (76.6) | |
| Histological type | Adenocarcinoma | 111 (100) |
| Histopathological grade | Moderately differentiated | 103 (92.8) |
| Poorly differentiated | 8 (7.2) | |
| Blood vessel invasion | Positive | 5 (4.5) |
| Negative | 106 (95.5) | |
| Metastatic type | Synchronous metastasis | 79 (71.2) |
| Metachronous metastasis | 32 (28.8) | |
| Metastatic site | Lung | 22 (19.8) |
| Liver | 79 (71.2) | |
| Brain | 2 (1.8) | |
| Peritoneum | 8 (7.2) | |
| K-ras gene | Wild type | 35 (46.1) |
| Mutant type | 41 (53.9) | |
| MMR/MSI status | d MMR (MSI-H) | 7 (6.3) |
| p MMR (MSI-L/MS-S) | 104 (93.7) | |
| Preoperative chemo/radiotherapy for synchronous metastasis | Yes | 13 (16.5) |
| No | 66 (83.5) |
Abbreviations: d MMR, deficient mismatch repair; p MMR, proficient mismatch repair; MSI-H, microsatellite instability-high; MSI-L, microsatellite instability-low; MS-S, microsatellite stability.