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. 2023 Jan 6;299(2):102874. doi: 10.1016/j.jbc.2023.102874

Table 1.

Summary of apparent dissociation constants for MLL1 core complex assembly at different temperaturesa

Temperature (°C) Kdapp (nM) Confidence interval (1σ)
5 7 6–9
10 7 5–11
15 20 13–30
20 30 22–39
25 62 51–72
30 290 204–417
37 6200 4900–7900
a

Dissociation constants and error estimates were obtained from fitting MWRAD2 concentration versus signal weight-average sedimentation coefficient (sw) using the A + B ⇋ AB heteroassociation model in SEDPHAT (59).