a) 10x brightfield image of indicated cultured APCs at confluence (Day 0), or 2 days (Day 2), or 4 days (Day 4) following the induction of in vitro adipocyte differentiation. APCs obtained from P28 Control and PpargTG mice treated with doxycycline (Dox) from P0.5-P7.5. Oil Red O staining of lipid accumulation and imaging was performed 4 days following the induction of differentiation.
b) mRNA levels of adipocyte-selective genes within differentiated cultures of APCs (Day 4) from P28 Control and PpargTG mice treated with doxycycline (Dox) from P0.5-P7.5. n=4, bars represent ± SEM. * denotes p<0.05 by student t-test.
Exact p values and numbers of repetitions can be found in Source Data Extended Data Figure 7.