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Association of CC16 mRNA expression levels in bronchial epithelial cells with (A and D) fractional exhaled nitric oxide (FeNO) values, (B and E) blood eosinophil counts, and (C and F) sputum percentage eosinophils in the SARP (Severe Asthma Research Program) cross-sectional and longitudinal cohorts. CC16 mRNA expression levels have been logarithm base 2 (log2)- and natural logarithm (ln)-transformed in the (A–C) SARP cross-sectional cohort and (D–F) longitudinal cohort, respectively.
