Table 2.
MR metrics in the OR of people with MS with and without prior ON.
| Participants with prior ON (N = 18) | Participants without prior ON (N = 12) | p-value | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Entire OR | NAWM | Lesion | Entire OR | NAWM | Lesion | Entire OR | NAWM | Lesion | |
| AVF | 0.2076 (0.0403) | 0.2124 (0.0348) | 0.1549 (0.0498) | 0.2510 (0.0461) | 0.2480 (0.0472) | 0.1624 (0.0456) | 0.01 | 0.03 | 0.71 |
| MVF | 0.2631 (0.0435) | 0.2674 (0.0369) | 0.2011 (0.0435) | 0.2708 (0.0313) | 0.2693 (0.0355) | 0.1978 (0.0397) | 0.60 | 0.89 | 0.85 |
| G-ratio | 0.6470 (0.0329) | 0.6472 (0.0302) | 0.6519 (0.0633) | 0.6756 (0.0385) | 0.6721 (0.0358) | 0.6630 (0.0614) | 0.04 | 0.05 | 0.67 |
MR: magnetic resonance; MS: multiple sclerosis; ON: optic neuritis; NAWM: normal-appearing white matter; AVF: axonal volume fraction; MVF: myelin volume fraction; OR: optic radiations; SD: standard deviation;
AVF, MVF, and g-ratio of the entire OR, NAWM, and lesions were reported as means with SD. Raw unadjusted p-values were reported here. No p-values survived Bonferroni correction.