Table 3.
Relationship between optical coherence tomography measures and MR metrics in the OR.
| AVF | MVF | G-ratio | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Entire OR | NAWM | Lesion | Entire OR | NAWM | Lesion | Entire OR | NAWM | Lesion | |
| RNFL | 0.632 (0.001*) | 0.531 (0.009*) | 0.514 (0.02) | 0.428 (0.04) | — | — | 0.382 (0.07) | — | — |
| GCIPL | 0.657 (0.001*) | 0.537 (0.008*) | 0.455 (0.04) | 0.582 (0.004*) | 0.444 (0.03) | 0.347 (0.13) | 0.267 (0.22) | — | — |
MR: magnetic resonance; OR: optic radiations; AVF: axonal volume fraction; MVF: myelin volume fraction; NAWM: normal-appearing white matter; RNFL: retinal nerve fiber layer; GCIPL: ganglion cell layer plus inner plexiform layer.
Pearson's correlation coefficients with raw unadjusted p-values were reported for AVF, MVF, and g-ratio correlations. Dash (—) denotes subanalysis was not performed because of the non-significance of the main result. P-values surviving Bonferroni correction are marked with an asterisk (*).