Table 6.

Crude and fully adjusted HR for mortality, respiratory failure, and ICU admission comparing patients with and without dementia

Characteristic	HR	95% CI	p value
Mortality
Crude HR mortality	1.86	1.21, 2.87	0.005
Fully adjusted HR for mortality
COVID-19 severitya
Mild	7.25	2.67, 19.68	<0.001
Severe	1.17	0.29, 4.71	0.828
Critical	0.86	0.52, 1.44	0.571
Confounders
Hypertension	0.87	0.79, 0.97	0.008
Age	1.01	1.01, 1.01	<0.001
Sex (male)	0.96	0.87, 1.06	0.443
Respiratory failure
Crude HR for respiratory failure	3.14	1.92, 5.15	<0.001
Fully adjusted HR for respiratory failure
COVID-19 severitya
Mild	<0.01	<0.01, <0.01	<0.001
Severe	0.96	0.13, 6.85	0.967
Critical	0.80	0.48, 1.33	0.387
Confounders
Smoker	1.29	1.13, 1.48	<0.001
Hypertension	1.98	1.76, 2.22	<0.001
Diabetes mellitus	1.31	1.17, 1.46	<0.001
Age	1.00	1.00, 1.00	0.940
Sex (male)	0.89	0.81, 0.99	0.033
ICU admission
Crude HR for ICU admission	3.46	2.18, 5.51	<0.001
Fully adjusted HR for respiratory failure
COVID-19 severitya
Mild	4.37	1.08, 17.63	0.038
Severe	0.61	0.09, 4.32	0.617
Critical	0.78	0.46, 1.30	0.332
Confounders
Smoker	1.37	1.20, 11.56	<0.001
Hypertension	2.24	2.00, 2.51	<0.001
Diabetes mellitus	1.39	1.25, 1.54	<0.001
Age	1.00	1.00, 1.00	0.539
Sex (male)	0.93	0.84, 1.03	0.161

HR, hazard ratio; 95% CI, 95% confidence interval; COVID-19, coronavirus disease 2019; ICU, intensive care unit.

^aInteraction term/effect-measure modification: likelihood ratio test p value <0.001.