Skip to main content
. Author manuscript; available in PMC: 2023 Feb 20.
Published in final edited form as: Science. 2019 Feb 8;363(6427):582–583. doi: 10.1126/science.aav0558

Figure 1. BCAAs: Biomarkers and causal agents of cardiometabolic disease.

Figure 1.

Diet, obesity, the gut microbiota, and genetics can increase circulating BCAAs. BCAAs are proposed to promote increased hepatic lipid storage, cardiac hypertrophy, and lipid accumulation contributing to muscle insulin resistance.