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Modes of Inheritance following Environmental Exposure. Exposure in gestational females (P0) also exposes the embryo (F1) and its germ cells (F2). Therefore, only the third generation is the one where the observed phenotype is not due to direct exposure and can truly be transgenerational. For post-natal exposure, as presented under the paternal scheme, exposure affects the F1, hence, the second generation is the one where transgenerational phenotypes can be observed.
