TABLE 3.
IC50 of P. cattleianum leaves (L) and flowers’ (F) essential oils against 5-LOX, COX-1, and COX-2 enzymatic activities.
| Tested EO | IC50 ± SD (µL/mL) | ||
|---|---|---|---|
| 5-LOX | COX-1 | COX-2 | |
| L | 2.38 ± 0.10 | 45.96 ± 2.32 | 9.116 ± 0.25 |
| F | 7.69 ± 0.22 | 19.08 ± 0.96 | 2.575 ± 0.07 |
| Indomethacin (µg/mL) | — | 1.067 ± 0.05 | 6.653 ± 0.18 |
| SC560 (nM) | — | 6.45 ± 0.05 | — |
| Celecoxib (µM) | — | 11.34 ± 0.57 | 0.547 ± 0.01 |
| Zileuton (µM) | 0.42 ± 0.02 | - | —- |