Table 1.

Inhibitors of PARP10

Drug	References	IC50 (μM)	Selectivity
Compound 19	Ekblad et al., 2015	2.0	>20-fold over PARP1/10/15
8b	Holecheck et al., 2018	0.4	Selective over PARP1
8r	Holecheck et al., 2018	0.39	Selective over PARP1
OUL35	Venkannagari et al., 2016	0.329	>12-fold selective against all members except PARP11
Compound 22	Morgan et al., 2019	1.8	Selective for PARP10