Table 1.

Subset of high delta score mutations passing binding sites thresholds

	RBP	Variant	Strain	Genomic element	REF score	ALT score	delta score	Impact
0	SRSF7	G210T	delta, kappa	5’ UTR	0.768	0.457	−0.311	loss
1	RBM20	C3267T	alpha	ORF1ab	0.813	0.336	−0.477	loss
2	RBM22	C18877T	mu	ORF1ab	0.338	0.614	0.276	gain
3	HNRNPC	C21575T	iota	S	0.374	0.840	0.467	gain
4	MBNL1	del_22281	beta	S	0.800	0.006	−0.795	loss
5	ELAVL1	del_22299	lambda	S	0.070	0.632	0.562	gain
6	SF3B4	del_22299	lambda	S	0.871	0.128	−0.744	loss
7	SF3A3	del_22299	lambda	S	0.860	0.273	−0.587	loss
8	U2AF2	del_22299	lambda	S	0.543	0.980	0.438	gain
9	GPKOW	del_22299	lambda	S	0.297	0.841	0.544	gain
10	MBNL1	del_22299	lambda	S	0.803	0.398	−0.405	loss
11	SF3A3	C22995A	omicron	S	0.081	0.808	0.726	gain
12	ORF1	A23013C	omicron	S	0.014	0.621	0.608	gain
13	ORF1	A23040G	omicron	S	0.006	0.673	0.666	gain
14	ORF1	G23048A	omicron	S	0.006	0.606	0.600	gain
15	SND1	G23048A	omicron	S	0.187	0.791	0.604	gain
16	SRSF7	C23604A	alpha, mu	S	0.394	0.719	0.326	gain
17	SRSF7	C23604G	delta, kappa	S	0.394	0.792	0.398	gain
18	HNRNPC	C25469T	delta, kappa	ORF3a	0.317	0.670	0.352	gain
19	FTO	G25563T	beta, epsilon, iota, mu	ORF3a	0.633	0.080	−0.552	loss
20	FTO	del_28278	eta	N	0.335	0.683	0.348	gain
21	FTO	G28280C	alpha	N	0.679	0.209	−0.470	loss
22	ORF1	A28699G	eta	N	0.597	0.141	−0.456	loss