Cytotoxicity of compounds 1 and 2.
| Compounds | IC50a(μM) | ||||||
|---|---|---|---|---|---|---|---|
| SKBR3 | HepG2 | A549 | J82 | MB49 (STR) | Huh7 | MB49 (WT) | |
| 1 | 49.2 ± 3.3 | 41.6 ± 8.1 | 4.3 ± 0.4 | 45.6 ± 2.5 | 49.3 ± 7.8 | 48.2 ± 5.6 | 43.3 ± 4.5 |
| 2 | 48.1 ± 6.5 | 41.2 ± 6.3 | 11.8 ± 2.8 | 48.7 ± 2.8 | 55.7 ± 10.8 | 44.1 ± 7.9 | 64.5 ± 6.7 |
| Cisplatinb | 3.6 ± 0.6 | 4.8 ± 0.9 | 6.5 ± 1.0 | 0.61 ± 0.1 | 9.6 ± 1.9 | 5.1 ± 1.6 | 5.1 ± 1.6 |
IC50 values were averaged from at least three independent experiments.
Positive control.