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. 2023 Feb 20;13(9):6124–6129. doi: 10.1039/d3ra00665d

Cytotoxicity of compounds 1 and 2.

Compounds IC50a(μM)
SKBR3 HepG2 A549 J82 MB49 (STR) Huh7 MB49 (WT)
1 49.2 ± 3.3 41.6 ± 8.1 4.3 ± 0.4 45.6 ± 2.5 49.3 ± 7.8 48.2 ± 5.6 43.3 ± 4.5
2 48.1 ± 6.5 41.2 ± 6.3 11.8 ± 2.8 48.7 ± 2.8 55.7 ± 10.8 44.1 ± 7.9 64.5 ± 6.7
Cisplatinb 3.6 ± 0.6 4.8 ± 0.9 6.5 ± 1.0 0.61 ± 0.1 9.6 ± 1.9 5.1 ± 1.6 5.1 ± 1.6
a

IC50 values were averaged from at least three independent experiments.

b

Positive control.