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. 2023 Jan 28;48:bjad001. doi: 10.1093/chemse/bjad001

Table 2.

Repeated measures ANOVA for peak signal change within 8 ROIs, for each response type during the ORM fMRI session.

ROI Hita CRa FAa Missa Sphericity (Mauchly’s test) Greenhouse–Geisser
Epsilon (ε)b 		Within-subjects effectsc Significant pairwise comparisonsd
Anterior insula Right 0.908 ± 0.047 1.05 ± 0.069 1.183 ± 0.093 1.029 ± 0.085 P = 0.259 Sphericity assumed P = 0.004* Hit vs. FA
(P = 0.006)
Left 0.663 ± 0.038 0.804 ± 0.071 0.949 ± 0.094 0.802 ± 0.1 P = 0.467 Sphericity assumed P = 0.001* Hit vs. FA
(P = 0.004)
Medial dorsal thalamus Right 0.8 ± 0.04 0.857 ± 0.077 0.91 ± 0.07 0.908 ± 0.074 P = 0.725 Sphericity assumed P = 0.210 —
Left 0.892 ± 0.041 0.999 ± 0.075 1.096 ± 0.08 1.055 ± 0.068 P = 0.739 Sphericity assumed P = 0.071 —
Middle frontal gyrus Right 0.546 ± 0.037 0.62 ± 0.061 0.664 ± 0.08 0.65 ± 0.066 P = 0.190 Sphericity assumed P = 0.077 —
Left 0.466 ± 0.043 0.612 ± 0.082 0.667 ± 0.106 0.628 ± 0.099 P = 0.002 ε = 0.732 P = 0.021* Hit vs. CR
(P = 0.037)
Posterior cingulate gyrus Right 0.253 ± 0.017 0.4 ± 0.033 0.412 ± 0.039 0.42 ± 0.047 P = 0.217 Sphericity assumed P < 0.001* Hit vs. CR
(P = 0.002)
Hit vs. FA
(P = 0.006)
Hit vs. Miss
(P = 0.034)
Left 0.316 ± 0.24 0.474 ± 0.37 0.471 ± 0.42 0.499 ± 0.54 P = 0.1 Sphericity assumed P < 0.001* Hit vs. CR
(P = 0.006)
Hit vs. FA
(P = 0.018)
Hit vs. Miss
(P = 0.04)
Precuneus Right 1.047 ± 0.069 1.177 ± 0.081 1.184 ± 0.077 1.263 ± 0.105 P = 0.036 0.755 P = 0.083 —
Left 1.504 ± 0.134 1.639 ± 0.137 1.710 ± 0.157 1.731 ± 0.146 P = 0.001 0.693 P = 0.278 —
Dentate gyrus Right 0.581 ± 0.051 0.687 ± 0.048 0.805 ± 0.079 0.742 ± 0.084 P = 0.085 Sphericity assumed P = 0.016* Hit vs. FA
(P = 0.005)
Left 0.454 ± 0.027 0.541 ± 0.031 0.644 ± 0.05 0.63 ± 0.064 P = 0.043 0.752 P = 0.021* Hit vs. FA
(P = 0.008)
Amygdala Right 0.892 ± 0.035 1.18 ± 0.058 1.303 ± 0.069 1.145 ± 0.128 P = 0.001 0.620 P = 0.007* Hit vs. CR
(P = 0.002)
Hit vs. FA
(P < 0.001)
Left 1.162 ± 0.052 1.584 ± 0.1 1.783 ± 0.116 1.363 ± 0.147 P = 0.011 0.720 P < 0.001* Hit vs. CR
(P < 0.001)
Hit vs. FA
(P < 0.001)
Posterior piriform cortex Right 1.234 ± 0.057 1.365 ± 0.043 1.682 ± 0.094 1.777 ± 0.204 P < 0.001 0.554 P = 0.018* Hit vs. FA
(P = 0.008)
Left 1.76 ± 0.07 2.488 ± 0.139 2.839 ± 0.182 2.217 ± 0.268 P < 0.001 0.609 P < 0.001* Hit vs. CR
(P < 0.001)
Hit vs. FA
(P < 0.001)
CR vs. FA
(P = 0.014)

aMean value ± standard error.

bEpsilon presented only if sphericity is not assumed (Mauchly’s test <0.05).

cIf sphericity is not assumed, the Greenhouse–Geisser results are presented for ε < 0.75 and the Huynh–Feldt results are presented for ε > 0.75.

dIncluding Bonferroni correction. Only significant results are presented.

*Statistical significance.