Table 3.
Multivariate logistic regression analysis of possible predicts of SAP
| Variables | aModel 1 | bModel 2 | ||
|---|---|---|---|---|
| Adjusted OR | P-value | Adjusted OR | P-value | |
| Age | 1.027(0.990–1.066) | 0.150 | 1.02(0.984–1.057) | 0.290 |
| NLR | 1.288(1.123–1.476) | <0.001* | 1.127(1.017–1.249) | 0.023* |
| Initial NIHSS score | 1.118(1.036–1.205) | 0.004* | 1.112(1.031–1.199) | 0.006* |
| Dysphagia | 18.859(7.282–48.839) | <0.001* | 14.576(5.708–37.218) | <0.001* |
| A2DS2 score | 1.656(1.4–1.959) | <0.001* | 1.574(1.331–1.863) | <0.001* |
| Atrial fibrillation | 4.387(1.110–17.341) | 0.035* | 6.523(1.826–3.298) | 0.004* |
| Hyperlipidemia | 1.087(0.479–2.469) | 0.842 | 0.974(0.44–2.156) | 0.948 |
| Diabetes mellitus | 1.543(0.694–3.431) | 0.288 | 1.958(0.883–4.338) | 0.098 |
| Previous stroke | 0.936(0.3–2.922) | 0.910 | 1.308(0.439–3.895) | 0.630 |
| Hypertension | 1.135(0.435–2.96) | 0.796 | 1.101(0.436–2.782) | 0.838 |
| Ischemic heart disease | 0.825(0.217–3.134) | 0.778 | 0.97(0.260–3.615) | 0.964 |
| Drinking | 0.720(0.276–1.881) | 0.503 | 0.588(0.233–1.486) | 0.262 |
| Smoking | 2.842(0.978–8.257) | 0.055 | 2.761(0.977–7.806) | 0.055 |
NIHSS National Institutes of Health Stroke Scale, NLR neutrophil-to-lymphocyte ratio, OR odds ratio, SAP stroke-associated pneumonia
aModel 1:NLR measured before IVT (within 30 min after admission)
bModel 2:NLR measured within 24–36 h after IVT
Model 1 and Model 2 were both adjusted with P < 0.1 in univariate analysis and diabetes mellitus, smoking, drinking, ischemic heart disease, hyperlipidemia, and stroke etiology
*p < 0.05