Table 5.Lung function and radiological data of patients with rheumatoid arthritis ACPA+(n=26)divided according to the rheumatoid factor (RF) status): Algiers (Algeria):2018-2019.
Data |
Outcome |
Unit/Category |
RF - (n=11) |
RF + (n=15) |
p-value |
FVC |
L |
2.35±0.80 |
2.53±0.84 |
.5760 |
|
% |
75±23 |
77±23 |
.8298 |
||
z-score |
-1.89±1.68 |
-1.85±1.82 |
.9525 |
||
FEV1 |
L |
1.83±0.69 |
1.78±0.83 |
.8694 |
|
% |
75±30 |
67±30 |
.4998 |
||
z-score |
-1.76±2.07 |
-2.47±2.20 |
.4166 |
||
MMEF |
L/s |
2.55±1.32 |
2.15±1.22 |
.4309 |
|
% |
116±66 |
84±51 |
.1750 |
||
z-score |
0.09±1.69 |
-1.03±2.10 |
.1571 |
||
SVC |
L |
2.46±0.93 |
2.67±0.88 |
.5715 |
|
% |
73±25 |
75±21 |
.7860 |
||
Lung function data |
z-score |
-2.16±1.91 |
-1.99±1.69 |
.8108 |
|
FRC |
L |
2.99±1.52 |
4.00±1.37 |
.0888 |
|
% |
115±47 |
161±60 |
.0443 * |
||
z-score |
0.44±1.82 |
2.30±1.98 |
.0218 * |
||
RV |
L |
2.23±1.27 |
3.09±1.41 |
.1220 |
|
% |
137±62 |
233±139 |
.0423 * |
||
z-score |
1.12±1.88 |
2.88±2.30 |
.0490 * |
||
TLC |
L |
4.62±1.86 |
5.74±1.39 |
.0916 |
|
% |
91±27 |
117±27 |
.0271 * |
||
z-score |
-0.88±2.29 |
1.22±2.08 |
.0224 * |
||
IC |
L |
1.67±0.54 |
1.76±0.49 |
.6746 |
|
% |
69±22 |
72±18 |
.7144 |
||
z-score |
-1.63±1.13 |
-1.48±0.94 |
.7048 |
||
FEV1/FVC |
AV |
0.79±0.13 |
0.68±0.13 |
.0424 * |
|
% |
99±17 |
83±17 |
.0292 * |
||
z-score |
-0.00±1.74 |
-1.68±1.59 |
.0178 * |
||
RV/TLC |
AV |
47.09±8.54 |
52.56±15.28 |
.2960 |
|
% |
151±37 |
191±70 |
.1029 |
||
z-score |
2.25±1.63 |
3.40±2.30 |
.1696 |
||
Bronchiectasis |
(yes) |
3 (27.3) |
6 (40.0) |
.5013 |
|
Bronchial wall thickening |
(yes) |
1 (9.1) |
1 (6.7) |
.8207 |
|
Thickened septal/non- septal lines |
(yes) |
6 (54.5) |
6 (40.0) |
.4637 |
|
Radiological data |
|||||
Interstitial lung disease |
(yes) |
9 (81.8) |
7 (46.7) |
.0691 |
|
Nonspecific interstitial pneumonia |
(yes) |
8 (72.7) |
5 (33.3) |
.0471 * |
|
Bronchiolitis |
(yes) |
6 (54.5) |
4 (26.7) |
.1500 |
|
Ground glass attenuation |
(yes) |
7 (63.6) |
7 (46.7) |
.3931 |
|
Usual interstitial pneumonia |
(yes) |
2 (18.2) |
1 (6.7) |
.3650 |
|
Micro nodule |
(yes) |
7 (63.6) |
9 (60.0) |
.8521 |
|
Air space consolidation |
(yes) |
6 (54.5) |
7 (46.7) |
.6943 |
ACPA: Anti-Citrullinated Peptides Antibodies. AV: Absolute Value. FEV 1: Forced Expiratory Volume in one second. FRC: Functional Residual Capacity. FVC: Forced Vital Capacity. IC: Inspiratory Capacity. MMEF: Maximal-Mid Expiratory Flow. RV: Residual Volume. SVC: Slow Vital Capacity. TLC: Total Lung Capacity. %: percent of predicted values. Quantitative and categorical data were mean±SD and number (%), respectively. * p-value < 0.05: 2 sided Chi-square test (comparison of categorical data between the 2 groups) Student's T test (comparison of quantitative data between the 2 groups).