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. 2022 Aug 1;100(8):626–641.

Table 5.Lung function and radiological data of patients with rheumatoid arthritis ACPA+(n=26)divided according to the rheumatoid factor (RF) status): Algiers (Algeria):2018-2019.

Data

Outcome

Unit/Category

RF - (n=11)

RF + (n=15)

p-value

FVC

L

2.35±0.80

2.53±0.84

.5760

%

75±23

77±23

.8298

z-score

-1.89±1.68

-1.85±1.82

.9525

FEV1

L

1.83±0.69

1.78±0.83

.8694

%

75±30

67±30

.4998

z-score

-1.76±2.07

-2.47±2.20

.4166

MMEF

L/s

2.55±1.32

2.15±1.22

.4309

%

116±66

84±51

.1750

z-score

0.09±1.69

-1.03±2.10

.1571

SVC

L

2.46±0.93

2.67±0.88

.5715

%

73±25

75±21

.7860

Lung function data

z-score

-2.16±1.91

-1.99±1.69

.8108

FRC

L

2.99±1.52

4.00±1.37

.0888

%

115±47

161±60

.0443 *

z-score

0.44±1.82

2.30±1.98

.0218 *

RV

L

2.23±1.27

3.09±1.41

.1220

%

137±62

233±139

.0423 *

z-score

1.12±1.88

2.88±2.30

.0490 *

TLC

L

4.62±1.86

5.74±1.39

.0916

%

91±27

117±27

.0271 *

z-score

-0.88±2.29

1.22±2.08

.0224 *

IC

L

1.67±0.54

1.76±0.49

.6746

%

69±22

72±18

.7144

z-score

-1.63±1.13

-1.48±0.94

.7048

FEV1/FVC

AV

0.79±0.13

0.68±0.13

.0424 *

%

99±17

83±17

.0292 *

z-score

-0.00±1.74

-1.68±1.59

.0178 *

RV/TLC

AV

47.09±8.54

52.56±15.28

.2960

%

151±37

191±70

.1029

z-score

2.25±1.63

3.40±2.30

.1696

Bronchiectasis

(yes)

3 (27.3)

6 (40.0)

.5013

Bronchial wall thickening

(yes)

1 (9.1)

1 (6.7)

.8207

Thickened septal/non- septal lines

(yes)

6 (54.5)

6 (40.0)

.4637

Radiological data

Interstitial lung disease

(yes)

9 (81.8)

7 (46.7)

.0691

Nonspecific interstitial pneumonia

(yes)

8 (72.7)

5 (33.3)

.0471 *

Bronchiolitis

(yes)

6 (54.5)

4 (26.7)

.1500

Ground glass attenuation

(yes)

7 (63.6)

7 (46.7)

.3931

Usual interstitial pneumonia

(yes)

2 (18.2)

1 (6.7)

.3650

Micro nodule

(yes)

7 (63.6)

9 (60.0)

.8521

Air space consolidation

(yes)

6 (54.5)

7 (46.7)

.6943

ACPA: Anti-Citrullinated Peptides Antibodies. AV: Absolute Value. FEV 1: Forced Expiratory Volume in one second. FRC: Functional Residual Capacity. FVC: Forced Vital Capacity. IC: Inspiratory Capacity. MMEF: Maximal-Mid Expiratory Flow. RV: Residual Volume. SVC: Slow Vital Capacity. TLC: Total Lung Capacity. %: percent of predicted values. Quantitative and categorical data were mean±SD and number (%), respectively. * p-value < 0.05: 2 sided Chi-square test (comparison of categorical data between the 2 groups) Student's T test (comparison of quantitative data between the 2 groups).