Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A low concentration of TNF-α promotes MSC mineralization and osteogenic differentiation by: inhibiting PPAR-γ activity and increasing TNAP expression and inducing the ubiquitination and degradation of GRK2 via its binding to Mdm2 and decreasing A2BAR desensitization.
