TABLE 3.
Incidence of adverse events across trial by treatment.
| Adverse event | Synbiotics | Probiotics | Placebo | Prebiotic diet | Total |
| Changes in bowel movements | 1 | 1 | 2 | 1 | 5 |
| Back and muscular pain | 1 | 2 | 3 | ||
| Bloating, gas, and abdominal discomfort | 4 | 2 | 1 | 7 | |
| Cold/flu symptoms and sinus issues | 3 | 1 | 2 | 6 | |
| Fatigue and soreness | 1 | 1 | 1 | 1 | 4 |
| Headaches | 1 | 2 | 2 | 5 | |
| Bronchitis | 1 | 1 | |||
| Physical anxiety | 1 | 1 | |||
| Vomiting, nausea, and dizziness | 2 | 1 | 3 | ||
| Swollen lymph nodes | 1 | 1 | |||
| Weight gain | 1 | 1 | |||
| Skin rash or fungal infections | 1 | 1 | |||
| Total (%) | 12 (31.6) | 10 (26.3) | 9 (23.7) | 7 (18.4) | 38 (100.0) |