TABLE 2.
Summary Statistics for Age, Hippocampal, and Hemisphere Volumes at T1, T2, and T3 (mm3) by Diagnosis and Sex
| TD-M (n = 60) |
ASD-M (n = 137) |
TD-F (n = 50) |
ASD-F (n = 63) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean | SD | n | Mean | SD | n | Mean | SD | n | Mean | SD | |
| T1 | ||||||||||||
| Age (mo) | 60 | 37.0 | 6.4 | 137 | 37.7 | 6.2 | 50 | 38.8 | 6.8 | 63 | 39.6 | 6.5 |
| L HV | 58 | 3,359.6 | 289.9 | 135 | 3,435.4 | 329.0 | 47 | 3,202.7 | 275.8 | 63 | 3221.8 | 351.2 |
| R HV | 58 | 3,541.1 | 286.6 | 135 | 3,653.4 | 352.8 | 47 | 3,390.3 | 288.5 | 63 | 3,438.1 | 348.2 |
| L hemisphere | 56 | 509,233.4 | 42,155.2 | 137 | 530,477.1 | 42,132.0 | 50 | 480,205.7 | 34,980.2 | 63 | 489,476.8 | 46,033.6 |
| R hemisphere | 56 | 516,058.6 | 42,158.3 | 137 | 538,973.9 | 41,830.3 | 50 | 483,933.1 | 35,870.5 | 63 | 493,670.1 | 45,429.9 |
| T2 | ||||||||||||
| Age (mo) | 43 | 50.4 | 6.5 | 81 | 50.1 | 6.3 | 28 | 51.8 | 6.1 | 28 | 54.7 | 7.3 |
| L HV | 43 | 3,584.8 | 289.6 | 81 | 3,647.6 | 366.0 | 28 | 3,387.9 | 278.0 | 28 | 3,466.8 | 329.4 |
| R HV | 43 | 3,773.1 | 300.8 | 81 | 3,863.2 | 364.7 | 28 | 3,576.9 | 268.0 | 28 | 3,663.8 | 318.7 |
| L hemisphere | 43 | 544,535.1 | 45,730.4 | 81 | 564,425.2 | 45,588.4 | 28 | 511,082.6 | 40,316.9 | 28 | 516,097.9 | 42,636.9 |
| R hemisphere | 43 | 550,376.6 | 45,373.3 | 81 | 570,366.1 | 45,577.5 | 28 | 514,474.0 | 41,922.1 | 28 | 520,072.2 | 40,647.1 |
| T3 | ||||||||||||
| Age (mo) | 29 | 61.6 | 5.1 | 50 | 63.8 | 5.8 | 20 | 65.5 | 6.8 | 13 | 67.7 | 6.3 |
| L HV | 29 | 3,786.0 | 272.8 | 50 | 3,849.3 | 361.8 | 20 | 3,593.5 | 344.4 | 13 | 3,605.4 | 397.5 |
| R HV | 29 | 3,905.7 | 243.7 | 50 | 4,046.6 | 405.4 | 20 | 3,725.9 | 303.8 | 13 | 3,758.0 | 433.3 |
| L hemisphere | 29 | 563,830.4 | 40,644.3 | 50 | 593,898.4 | 43,707.8 | 20 | 532,488.3 | 35,573.8 | 13 | 533,039.8 | 45,662.0 |
| R hemisphere | 29 | 566,987.2 | 40,125.9 | 50 | 597,425.9 | 43,129.3 | 20 | 535,659.9 | 36,030.4 | 13 | 535,762.8 | 44,505.9 |
Note: Hippocampus and hemisphere volumes are expressed in cubic millimeters (mm3). ASD = autism spectrum disorder; ASD-F = ASD female participants; ASD-M = ASD male participants; HV = hippocampal volume; L = left; R = right; T1 = time 1; T2 = time 2; T3 = time 3; TD = typically developing; TD-F = TD female participants; TD-M = TD male participants.