Table 5.
Comparison of study-determined MSI predominance: quantitative speech measures versus auditory-perceptual ratings (MSI+ group only).
| Group | Case | Syndrome dx | Quantitative MSI predominance (AOS + , Dys + ) a | Auditory-perceptual MSI predominance (AOS + , Dys + ) b |
|---|---|---|---|---|
| MSI+ | 10 | PPAOS | Dys + | Dys + |
| 11 | nfvPPA | AOS + | AOS + | |
| 12 | CBS | AOS + | AOS + | |
| 13 | PSP | Dys+ | AOS+ | |
| 14 | nfvPPA | AOS + | AOS + | |
| 15 | PSP | Dys + | Dys + | |
| 16 | PPAOS | AOS + | AOS + | |
| 17 | PPAOS | AOS + | AOS + | |
| 18 | PPAOS | AOS + | = | |
| 19 | CBS | AOS+ | Dys+ | |
| 20 | nfvPPA | Dys + | Dys + |
Note. Bold text indicates agreement (bold = agree; nonbold = disagree) between predominance rating given by quantitative features as compared with auditory-perceptual rating. Italicized text (Case 18) indicates that agreement could not be assessed because auditory-perceptual ratings did not establish a predominance of either AOS or dysarthria. dx = diagnosis; AOS = apraxia of speech; Dys = dysarthria; MSI+ = motor-speech–impaired group of individuals with nfvPPA, PPAOS, CBS, or PSP and suspected four-repeat tauopathy pathology; PPAOS = primary progressive apraxia of speech; nfvPPA = nonfluent variant primary progressive aphasia; CBS = corticobasal syndrome; PSP = progressive supranuclear palsy.
Predominant impairment based on quantitative speech features, rated for the MSI+ group only. Predominance determined from a ratio of mean |z|, AOS features to mean |z|, dysarthria features. AOS + (|z|AOS > |z|dys) indicates predominant apraxic impairment; Dys + (|z|dys > |z|AOS) indicates predominant dysarthric impairment.
Predominant impairment based on independent auditory-perceptual ratings, rated for the MSI+ group only. Predominance determined from a ratio of mean (across two speech-language pathologist raters) scores for AOS to dysarthria severity. “AOS+” (i.e., mean rated severity AOS > Dys) indicates predominant apraxic impairment; “Dys+” (i.e., mean rated severity Dys > AOS) indicates predominant dysarthric impairment; “=” (i.e., mean rated severity AOS = Dys) indicates no predominance of either apraxia or dysarthria.