Table 1.
Clinical, hormonal, and metabolic features of normal weight PCOS patents and obesity/overweight PCOS patents.
| Variable | PCOS | p | |
|---|---|---|---|
| Normal weight (n = 525) | Obesity/overweight (n = 428) | ||
| Age (y) | 27.08 ± 3.32 | 27.48 ± 3.59 | 0.076 |
| BMI (kg/m2) | 21.05 ± 1.67 | 27.73 ± 3.16 | 0.0001 |
| WHR | 0.84 ± 0.07 | 0.92 ± 0.37 | 0.0001 |
| WHtR | 47.49 ± 4.45 | 57.90 ± 5.78 | 0.0001 |
| E2 (pmol/l) | 158.15 ± 77.81 | 150.66 ± 77.94 | 0.140 |
| T (nmol/l) | 1.15 ± 0.60 | 1.21 ± 0.60 | 0.143 |
| LH/FSH ratio | 1.71 ± 1.09 | 1.33 ± 0.72 | 0.0001 |
| SHBG (nmoL/l) | 56.21 ± 38.07 | 33.55 ± 28.94 | 0.0001 |
| FAI | 3.00 ± 3.06 | 5.39 ± 4.23 | 0.0001 |
| FGS (mmol/l) | 5.47 ± 0.84 | 6.02 ± 1.18 | 0.0001 |
| F2h (mmol/l) | 5.99 ± 1.57 | 7.45 ± 2.21 | 0.0001 |
| FIN (μIU/ml) | 10.29 ± 6.29 | 18.68 ± 8.99 | 0.0001 |
| FI2h (μIU/ml) | 75.66 ± 73.52 | 133.78 ± 145.50 | 0.0001 |
| HOMA-IR | 2.55 ± 1.73 | 5.14 ± 2.98 | 0.0001 |
| CHO (mmol/l) | 4.17 ± 0.72 | 5.37 ± 0.49 | 0.179 |
| TG (mmol/l) | 1.17 ± 0.96 | 1.84 ± 1.19 | 0.0001 |
| HDL-C (mmol/l) | 1.36 ± 0.29 | 1.13 ± 0.23 | 0.0001 |
| LDL-C (mmol/l) | 2.69 ± 1.3 | 2.77 ± 1.82 | 0.831 |
| LP (a) (mg/l) | 145.33 ± 142.28 | 153.02 ± 177.82 | 0.459 |
| VAI | 1.93 ± 2.39 | 3.60 ± 3.10 | 0.0001 |
| LAP | 26.72 ± 35.84 | 70.24 ± 57.38 | 0.0001 |
Note: values are expressed as mean ± SD. BMI: body mass index; WHR: waist-to-hip ratio; WHtR: waist-to-height ratio; E2: estradiol; T: testosterone; LH: luteinizing hormone; FSH: follicle-stimulating hormone; SHBG: sex hormone-binding globulin; FAI: free androgen index; FGS: fasting glucose; FIN: fasting insulin; F2h: 2-hour postprandial blood glucose; FI2h: 2-hour postprandial blood insulin; HOMA-IR: homeostasis model assessment-insulin resistance; CHO: total cholesterol; TG: triglyceride; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; LP (a): lipoprotein (a); VAI: visceral adiposity index; LAP: lipid accumulation product.